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CAG repeat length variation in the androgen receptor gene is not associated with spermatogenic failure.

Westerveld H, Visser L, Tanck M, van der Veen F, Repping S

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, the Netherlands. g.h.westerveld@amc.uva.nl

Previous association studies that described the effect of an enlarged CAG repeat length in the Androgen Receptor (AR) gene on spermatogenesis could not prove or refute a true association because of methodological weaknesses. Here, we clearly show that there is no association between CAG repeat length variation and semen quality.

Published 14 January 2008 in Fertil Steril, 89(1): 253-9.
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