Infertility Research Today is a free monthly online journal that collates and summarizes the latest research about Infertility, including details on male and female infertility, treatment, causes, pregnancy.

Pregnancy after tumor debulking and intraperitoneal cisplatin for appendiceal carcinoid tumor.

Smaldone GM, Richard SD, Krivak TC, Kelley JL, Edwards RP

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. mantiagm@upmc.edu

BACKGROUND: Pregnancy after cytoreductive surgery and intraperitoneal chemotherapy is rare. CASE: We present the case of a 25-year-old woman with appendiceal carcinoid tumor treated with intraperitoneal cisplatin for peritoneal recurrence after a fertility-sparing cytoreductive procedure. Five years after her procedure, she conceived with the help of assisted reproductive technologies and delivered a viable term fetus via cesarean delivery. She subsequently had a successful second pregnancy and is currently alive without evidence of her disease. CONCLUSION: Conception is possible after tumor debulking and intraperitoneal chemotherapy. In unique clinical situations, fertility-sparing surgery may be considered in young patients who desire future pregnancy.

Published 1 August 2007 in Obstet Gynecol, 110(2): 477-9.
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