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Impact of subgroup analysis on estimates of infertility.

Thornton KL, Goldman MB

Divison of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Reproductive Biology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA. kim.thornton@bostonivf.com

Conclusions regarding estimates of infertility may reflect study bias based on the definition of infertility used. Careful consideration of how the infertile population is defined, as well its use in subgroup analysis that may not be generalizable to the population of infertile women as a whole, is needed.

Published 5 September 2006 in Fertil Steril, 86(3): 531-3; discussion 534.
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