Infertility Research Today is a free monthly online journal that collates and summarizes the latest research about Infertility, including details on male and female infertility, treatment, causes, pregnancy.

Insulin growth factors may be implicated in human sperm capacitation.

Sánchez-Luengo S, Fernández PJ, Romeu A

Human Reproduction Department, Hospital la Fe, Avda Campanar 21, 46009 Valencia, Spain. sslvalencia@lycos.es

This study was designed to determine whether or not insulin-like growth factor (IGF)-1 and its receptor are present in the human male genital tract. The IGF-1 receptor was found in seminal plasma from fertile and infertile men, but no IGF-1 receptor was observed in sperm from patients with a history of more failed fertilization. The presence of the IGF-1 receptor in the plasma membrane of human sperm is proposed as a future tool for male sterility assessment.

Published 11 April 2005 in Fertil Steril, 83(4): 1064-6.
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